Xodol, made by Accentia Biopharmaceuticals, Inc., is essentially a new formulation of Vicodin, with a lower amount of APAP. This allows patients to take more of the medication in a single day, since APAP use should be limited to 4000 mg/day.
The new formulation, which contains 10 mg of hydrocodone and 300 mg of APAP per tablet, (The most common form of Vicodin is 5/500.), will help patients to take more advantage of the pain relieving properties of the hydrocodone, without having to worry about APAP intake.
Reed the article at PharmacyOneSource.com. (Free subscription required.
Pain Relief, Xodol, Vicodin, FDA Approval
Can Xodol cause depression if one is taking 4 to 5 tablets a day?
According to the drug’s web site (www.xodol.com) and ePocrates, depression is not listed as a side effect of acetaminophen/hydrocodone combinations (including xodol, Vicodin, and Lortab). However, they may cause an “additive CNS depression” when used in combination with alcohol and other CNS depressants.
Please remember that I am not a pharmacist (just a technician so far), and therefore cannot provide any clinical advice. If you are experiencing depression in connection with Xodol, you should consult with your doctor or pharmacist.
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